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          Bringing the near future to light.

            Our portfolio companies are harnessing the power of computation to reprogram, engineer, scale, digitize, miniaturize, visualize, and grow the future.
              * A-ALPHA BIO
                Accelerating therapeutic discovery by measuring millions of protein-protein interactions at a time
              * APPIA BIO
                Scaling manufacturing to unlock the promise of off-the-shelf cell therapies
              * CANAERY
                Building a nose-computer interface to decode the hidden world of scent
              * CELLCHORUS
                High throughput single-cell analysis for development of cell therapies
              * CHECKERSPOT
                Synthetic biology and chemistry to produce novel bio-derived oils from microalgae
              * COPERNIC CATALYSTS
                Using physics-based computational modeling to design catalysts for sustainable drop-in chemicals and efuels
              * CYTOVALE
                Clinical diagnostics to measure biophysical markers of single cells
              * ECOVATIVE DESIGN
                Mycelium technology driving plant-based meats, biodegradable packaging and textiles
              * ENPLUSONE BIO
                Harnessing the power and flexibility of enzymes to deliver RNA to the world
              * IMMUSOFT
                Genetically modifying B cells to create sustained, protein-producing therapeutics in the body
              * INCENDIA THERAPEUTICS
                Novel therapeutic platform reprogramming the tumor microenvironment for recalcitrant tumors
              * MODERN MEADOW
                Building enhanced functionality through biofabrication
              * NOETIK
                Leveraging advanced machine learning methods to discover and develop cancer immunotherapies
              * PARALLEL BIO
                Putting the immune system in a dish to improve drug discovery
              * PASSKEY THERAPEUTICS
                Discovering multifunctional drugs for common-yet-complex diseases through advanced computation
              * PHANTOM NEURO
                Building a system to help people control robotic limbs using low-risk implantable sensors, AI, and enabling software
              * SHIRATRONICS
                Novel neuromodulation technologies to combat debilitating migraine headaches
              * STRM.BIO
                Leveraging extracellular vesicles to deliver gene therapies in-vivo
              * SURF BIO
                A stabilization platform that addresses some of drug delivery’s most difficult challenges
              * TFC THERAPEUTICS
                Targeting foundational cancer cells to develop better therapies
              * TWELVE
                Transforming industrial carbon dioxide emissions into useful chemicals
              * VITRA LABS
                Reimagining fertility with next generation IVF
              * ZYMOCHEM
                Developing microbes and bioprocesses for the sustainable and profitable production of chemicals from renewable resources
        PREVIOUSLY

        Breakout Labs

          This isn’t our first rodeo. As founders of Breakout Labs at the Thiel Foundation, we have a long history of investing in and coalescing the ecosystem for early-stage, deep science companies.
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    Read more about our portfolio.

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