* About
            * Portfolio
            * Team
            * Feed
            * Connect
            * LP Login
            Explore Alta Partners
            * About
            * Portfolio
            * Team
            * Feed
            * Connect
            * LP Login
          Privacy Legal

                Innovation Leads to Disruption

                  Read The Success Story
                  Read The Success Story
                  Read The Success Story

                Curative Therapeutics and Novel Healthcare Delivery Models

                  The end goals are the same: improved patient outcomes and quality of life. Above all, we seek to partner with driven, engaging entrepreneurs, solving the world’s difficult problems.

                      Technology enabled solutions and services that fundamentally improve delivery and quality of care.
                      Application of revolutionary scientific discoveries to cure or radically change disease.
                      Strong entrepreneurs who are brave and talented enough to take on large and significant problems.

                Recent Life Sciences Investments

                          Redwood City, CA
                        View Website
                          Allakos, Inc.
                            Life Sciences
                            Public (NASDAQ: ALLK)
                            APNG I
                            AP VIII

                          Allakos is a clinical-stage biotechnology company developing therapies to treat a variety of allergic and inflammatory diseases. Allakos is primarily focused on eosinophilic gastrointestinal disorders (EGIDs), leveraging industry-leading expertise in eosinophil and mast cell biology. The Company’s lead candidate, antolimab, is currently being tested in clinical trials across several gastrointestinal, skin and ophthalmic diseases.

                        Read the Allakos Story
                          Cambridge, MA
                          Ally Therapeutics
                            Life Sciences
                            Private
                            APNG II

                          Ally Therapeutics is a biotechnology company dedicated to solving the immune response issues that limit the safety and efficacy of in vivo gene therapies

                          Boston, MA
                        View Website
                          Amplitude Therapeutics, Inc.
                            Life Sciences
                            Private
                            APNG III

                          Amplitude Therapeutics, Inc. is a private company founded by Cory Sago, Ph.D., and seeded by Arch Venture Partners and Alta Partners. The Board consists of Cory Sago, Julie Sunderland, and Jay Parrish, a founder of VIR Biotechnology with Arch and Alta.

                          Cory has been working with Amplifying RNA for its use in vaccines that may require the characteristics of Amplifying RNA rather than traditional mRNA for therapeutic dosing. There are potential applications in 4 areas, and Amplitude is conducting experiments to guide the strategy going forward.

                          Cambridge, MA
                        View Website
                          Be Biopharma
                            Life Sciences
                            Private
                            APNG II

                          Be Biopharma is a leader in developing B cells as medicines, treating disease with the human body’s native protein factories. The Company is precisely engineering B cells to harness their intrinsic drug-like properties – remarkable protein production, selective tissue targeting, and fine control of their cellular environment – to forge a new category of cell therapy.

                          San Mateo, CA
                        View Website
                          CuraSen Therapeutics
                            Life Sciences
                            Private
                            APNG I

                          CuraSen Therapeutics, Inc. is developing drugs targeting a novel mechanism in the brain to restore function, improve symptoms and modify disease in a range of neurodegenerative diseases, including orphan disorders as well as Parkinson’s Disease and Alzheimer’s Disease.

                          Cambridge, MA
                        View Website
                          DEM Bio
                            Life Sciences
                            Private
                            APNG III

                          DEM Bio is pioneering the next generation of immunotherapeutics designed to unleash macrophages and other myeloid effector cells to eliminate tumors by targeting novel ‘don’t eat me’ (DEM) and ‘eat me’ (EM) signals on cancer cells and macrophages. Their proprietary CHoMP™ platform (Co-culture with Human Myeloid Phagocytes) will be used to identify unexplored DEM and EM signals in a systematic and unbiased manner via inter-cellular CRISPR screening using tumor cells, primary macrophages, and other innate immune effector cells.

                          Brookline, MA
                        View Website
                          Edgewood Oncology, Inc.
                            Life Sciences
                            Private
                            APNG IV

                          Edgewood Oncology, Inc. was formed to develop BTX-A51, a novel oral multi-kinase inhibitor targeting CK1 and CDK7/9 that activates apoptosis by upregulating p53 and inactivating MCL-1, MYC, and MDM2, in AML, Sarcomas, and Solid Tumors. The compound has been in the clinic and appears to have a unique profile among kinase inhibitors.

                          Cambridge, MA
                        View Website
                          eGenesis
                            Life Sciences
                            Private
                            APNG I

                          eGenesis is revolutionizing the field of transplantation with an unparalleled, multiplexed gene editing platform for the development of human-compatible organs, tissues and cells. Harnessing the latest gene editing techniques, eGenesis has the capability to solve the global organ crisis by providing an alternative to allotransplantation. eGenesis is uniquely positioned to reinvigorate the field of xenotransplantation by addressing both the key virology and immunology hurdles that have impeded its advancement to date and provide commercially-viable products to save and enhance the lives of patients in need

                          Cambridge, MA
                        View Website
                          ImmuneID
                            Life Sciences
                            Private
                            APNG III

                          ImmuneID is a precision immunology company using its proprietary platform to simultaneously identify and therapeutically target millions of antibody interactions that drive immune diseases. The Company is employing its massively parallel, multiplexed, and unbiased systems to develop therapeutics for autoimmunity, severe allergy, oncology and infectious disease.

                          Cambridge, MA
                        View Website
                          Kelonia
                            Life Sciences
                            Private
                            APNG III

                          Kelonia’s lentiviral vector gene delivery platform uses a simple and elegant solution that builds on decades of research, development, and technical experience to and efficiently deliver genetic cargo only to the desired tissue.

                          San Diego, CA
                          Lassen Therapeutics
                            Life Sciences
                            Private
                            APNG II

                          Lassen Therapeutics is a San Diego based developer of antibody therapeutics intended to address serious unmet medical needs. The company is currently operating in stealth mode.

                          San Diego, CA
                        View Website
                          MBrace Therapeutics
                            Life Sciences
                            Private
                            APNG III

                          MBrace utilizes a unique antibody discovery methodology called SPARTA. SPARTA combines an in vitro screening step of a naïve human antibody library against tumor targets, with in vivo selections based on tumor-homing capabilities of a pre-enriched antibody pool. This unique approach overcomes several rate-limiting challenges for rapid translation into clinical applications.

                          South San Francisco, CA
                        View Website
                          Novome Biotechnologies
                            Life Sciences
                            Private
                            APNG II

                          Novome Biotechnologies, Inc. is a biotechnology company focused on engineering defined activities into the human gut microbiota to treat chronic diseases. The Company has developed the first-ever platform for controlled colonization of the gut with engineered bacteria, enabling first-in-class living therapeutics: Genetically Engineered Microbial Medicines (GEMMs).

                          Watertown, MA
                        View Website
                          Progentos Therapeutics
                            Life Sciences
                            Private
                            APNG IV

                          Progentos is developing first-in-class compounds to induce endogenous oligodendrocyte progenitor cells to remyelinate axons in patients suffering from MS and other demyelinating diseases. Combining expertise in chemistry, biology and in vivo models, Progentos discovers and develops novel small-molecule drugs to regenerate tissues in patients with degenerative diseases.

                          Hangzhou, China
                        View Website
                          Qihan Biotech
                            Life Sciences
                            Private
                            APNG I

                          Qihan Biotech is a biopharmaceutical company focusing on genetic editing for xenotransplantation. The Company’s services address the global shortage of organ donors, enabling patients to get required and matched organs when needed and lead a healthy life.

                          Carlsbad, CA
                        View Website
                          Tyra Biosciences
                            Life Sciences
                            Private
                            APNG II

                          Tyra Biosciences is an Alta-incubated biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.Tyra is combining insights from structure-based drug design (SBDD), kinase biology, computational chemistry and smart clinical development to discover and develop next-gen small molecule therapies that are active against both wild type and mutant targets

                          Seattle, WA
                        View Website
                          Variant Bio
                            Life Sciences
                            Private
                            APNG II

                          Variant Bio is developing therapies that will improve global health by studying the genes of people who are outliers for medically relevant traits.

                          San Francisco, CA
                        View Website
                          Vir Biotechnology
                            Life Sciences
                            Public (NASDAQ: VIR)
                            APNG I

                          Vir Biotechnology is a clinical-stage immunology company focused on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. Vir has assembled four technology platforms that are designed to stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Its current development pipeline consists of five product candidates targeting hepatitis B virus, influenza A, human immunodeficiency virus, and tuberculosis

                        Read the Vir Story

                Recent Healthcare Technology and Services Investments

                          Boston, MA
                        View Website
                          BetterVet
                            Healthcare Services
                            Private
                            APNG III

                          BetterVet is a full-service veterinary practice on wheels supported by a powerful digital
                          platform.


                          Denver, CO
                        View Website
                          DispatchHealth
                            Healthcare Services
                            Private
                            APNG I

                          DispatchHealth is redefining health care delivery to offer on-demand care for people of all ages in the comfort of their own home. DispatchHealth’s board-certified medical teams are equipped with all the tools necessary to treat common to complex injuries and illnesses. DispatchHealth works closely with payers, providers, health systems and others to deliver care in the home to reduce unnecessary emergency room visits and hospital readmissions.

                        Read The Dispatch Story
                          Denver, CO
                        View Website
                          Everside Health
                            Healthcare Services
                            Private
                            APNG I

                          Everside Health, formerly Paladina Health, is the second largest direct primary care provider in the U.S., operating 350 health clinics in 32 states located at or near the facilities of its employer, union and other benefit sponsor clients. Everside’s data-driven, patient-centric healthcare delivery model aligns incentives to benefit the patient, the physician and the benefit provider, all while reducing the total cost of care. Patients receive convenient, low- or no-cost access to physicians and 24/7 virtual care, reducing the need for costly ER use.

                          Pittsburgh, PA
                        View Website
                          Free Market Health
                            Healthcare Services
                            Private
                            APNG III

                          Free Market Health is a healthcare technology company dedicated to improving the specialty pharmacy ecosystem with a care-driven marketplace platform.


                          Cambridge, MA
                        View Website
                          PatientsLikeMe
                            Healthcare Services
                            Private
                            APNG II

                          PatientsLikeMe is an online patient community portal, consisting of an online platform offering those with a chronic condition the opportunity to track and share symptoms and treatment experiences, contribute data for research and connect with others who are going through similar situations.

                          Austin, TX
                        View Website
                          Harbor Health
                            Healthcare Services
                            Private
                            APNG IV

                          Harbor Health was created by people who have spent decades trying to make health better, including those who provide health to those who figure out how to pay for it. Harbor Health’s mission is to make the entire health system work better for consumers so that everyone can achieve optimal health.

                          San Francisco, CA
                        View Website
                          Transcarent
                            Healthcare Services
                            Private
                            APNG II

                          Transcarent is a consumer digital health company that uses a combination of software, technology, and data science to empower consumers with information and access, leading to better outcomes and more cost-effective decisions.

                          Atlanta, GA
                        View Website
                          United Musculoskeletal Partners Holdings, LLC ("UMP")
                            Healthcare Services
                            Private
                            APNG III

                          United Musculoskeletal Partners Holdings is a private orthopedics company currently with three large metropolitan markets, multiple outpatient surgical facilities, orthopedics hospitals, and ancillary services, including radiology and physical therapy.

                    View Past Portfolio

                      Life Sciences

                          Applied Genetic Technologies Corp.
                          aTyr Pharma
                          Avid Radiopharmaceuticals
                          Bioventus
                          Calistoga Pharmaceuticals
                          Centrexion
                          ChemGenex Pharmaceuticals
                          Esperion Therapeutics
                          Excaliard Pharmaceuticals
                          Immune Design Corp.
                          Kiadis Pharma
                          Kite Pharma
                          Lumena Pharmaceuticals
                          Neothetics
                          Prolacta Bioscience
                          Repros Therapeutics
                          SARcode Bioscience
                          Sutro Biopharma
                          Taligen Therapeutics
                          Trevena
                          Vertiflex
                          Zafgen
                          ZS Pharma
                          ACLARA Biosciences
                          Aegerion Pharmaceuticals
                          Aerie Pharmaceuticals
                          Agensys
                          Angiosyn
                          Astex Pharmaceuticals
                          Cellective Therapeutics
                          Chimerix
                          Cotherix
                          Cutera
                          Dynavax
                          Endonetics
                          Eyetech Pharmaceuticals
                          Flamel Technologies
                          FoldRx Pharmaceuticals
                          ILEX Oncology
                          InterMune Pharmaceuticals
                          Kosan Bioscience
                          LJL BioSystems
                          MacroGenics
                          Plexxikon
                          Swedish Orphan Biovitrum
                          Triangle Pharmaceuticals
                          U3 Pharma

                      Healthcare

                          ATS Medical
                          MAKO Surgical
                          Sierra Surgical Technologies
                          Definity Health
            Choose an option below to login.
            Alta Partners NextGen Funds LP Portal
            Explore Alta Partners
            * About
            * Portfolio
            * Team
            * Feed
            * Connect
            * LP Login
          Privacy Legal
          Take the lift?