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                      Portfolio

                      Growing Together

                      Meet our innovative medical device, diagnostic, life science, and tech-enabled services portfolio

                            * Current Companies
                            * Historic/Public Companies
                                  * All
                                  * Current Investments
                                      + Life Science Tools/Diagnostics
                                      + Medical Devices
                                      + Pharma Adjacencies
                                      + Tech-Enabled Care Delivery
                                  * Exits
                                      + Life Science Tools/Diagnostics
                                      + Medical Devices
                                      + Pharma Adjacencies
                                      + Tech-Enabled Care Delivery

                                              Akadeum Life Sciences

                                              Akadeum has developed a biological sample separation platform using buoyant microbubbles.

                                              Allay Therapeutics

                                              Allay Tx is developing a drug-eluting biopolymer for sustained post-operative orthopedic pain management.

                                              ArborMetrix

                                              ArborMetrix is a healthcare data analytics firm that offers software and services to help hospitals, health plans, and professional societies improve quality and costs.

                                              AtaCor Medical

                                              AtaCor is a medical device company pioneering new approaches to extravascular cardiac rhythm management.

                                              Avation Medical

                                              Avation Medical is pioneering non-surgical neuromodulation solutions to treat a variety of clinical conditions.

                                              Boomerang Medical

                                              Boomerang is developing a technology to advance the treatment of autoimmune diseases by harnessing the body’s own “peripheral wiring” to manage inflammation and immune response.

                                              BrightSpec

                                              BrightSpec is a life science tools company commercializing instruments for molecular structure characterization

                                              Cardiac Dimensions

                                              Cardiac Dimensions is selling a device for percutaneous mitral valve repair.

                                              ConcertoCare

                                              ConcertoCare is a full service home-based primary care practice focused 100% on seniors and older adults.

                                              Convergent Dental

                                              Convergent Dental offers the Solea® all-tissue laser for various anesthesia-free dental procedures and applications.

                                              Enumera Molecular

                                              Enumera Molecular is developing a rapid, low-cost molecular counting platform for clinical diagnostics.

                                              Flosonics Medical

                                              Flosonics Medical has developed a single-use ultrasound patch, FloPatch, for hemodynamic monitoring.

                                              Francis Medical

                                              Francis Medical is focused on using convective thermal water vapor to treat prostate, kidney, and bladder cancer.

                                              Hicuity Health

                                              Hicuity Health (fka Advanced ICU Care) provides remote ICU services to community hospitals.

                                              JUMPCODE Genomics

                                              JUMPCODE Genomics is a life science tools company developing reagent kits for improving sensitivity and reducing the cost of next-generation sequencing (NGS).

                                              Koya Medical

                                              Koya Medical is developing a novel active compression treatment for lymphedema and venous insufficiency.

                                              Motif Neurotech

                                              Motif Neurotech is pioneering wireless minimally-invasive neuromodulation therapeutics for mental health.

                                              Navv Systems

                                              Navv Systems has developed an indoor navigation and location services platform called NavvTrack® that enables hospitals and other healthcare organizations to better track equipment, personnel, and clinical workflows.

                                              Orasis Pharmaceuticals

                                              Orasis Pharmaceuticals is an ophthalmic pharmaceutical company with a prescription eye drop, Qlosi, for presbyopia.

                                              PAK BioSolutions

                                              PAK BioSolutions offers automated systems for continuous biopharmaceutical manufacturing.

                                              RareCyte

                                              RareCyte is a precision biology solution focused on the multiplexed analysis of cells and tissue with applications in both research and clinical diagnostics.

                                              Reprieve Cardiovascular

                                              Reprieve is a medical technology company developing a diuretic treatment device for acute decompensated heart failure (ADHF) patients.

                                              Shoulder Innovations

                                              Shoulder Innovations is a shoulder arthroplasty device company with an implant system for total and reverse shoulder replacements.

                                              SonarMD

                                              SonarMD is developing a subspecialty practice platform that improves care quality and lowers cost.

                                              Strata Oncology

                                              Strata Oncology has developed a solution for improving the delivery of precision oncology care.

                                              ViaLase

                                              ViaLase uses an image-guided femtosecond laser surgical system for the treatment of glaucoma.

                                              Virtual Incision

                                              Virtual Incision is developing a miniaturized surgical robotics system to perform GI and gynecology procedures. The size and functionality of the MIRA system will help bring robotic surgery to more patients and more sites both inside and outside the hospital.

                                              VYDENCE Medical

                                              VYDENCE develops, manufactures, and commercializes medical devices for aesthetic procedures in dermatology, plastic surgery, venous disease, and other specialties.

                                  * All
                                  * Current Investments
                                      + Life Science Tools/Diagnostics
                                      + Medical Devices
                                      + Pharma Adjacencies
                                      + Tech-Enabled Care Delivery
                                  * Exits
                                      + Life Science Tools/Diagnostics
                                      + Medical Devices
                                      + Pharma Adjacencies
                                      + Tech-Enabled Care Delivery

                                              Accuri Cytometers

                                              Acquired by Becton, Dickinson and Company, March 2011

                                              BioIQ

                                              Acquired by LetsGetChecked, May 2022

                                              CardioMEMS

                                              Acquired by St. Jude Medical, June 2014

                                              Dropworks

                                              Acquired by Bio-Rad Laboratories, October 2021

                                              Esperion Therapeutics

                                              Completed Initial Public Offering on June 26, 2013.

                                              EQRx

                                              Completed a SPAC merger in December 2021 to become a public company

                                              HandyLab

                                              Acquired by Becton, Dickinson and Company, November 2009.

                                              HealthMedia

                                              Acquired by Johnson & Johnson, October 2008.

                                              Inogen

                                              Completed Initial Public Offering on February 14, 2014.

                                              IntelliCyt

                                              Acquired by Sartorius, June 2016.

                                              MyHealthDirect

                                              Acquired by Experian Health, August 2019.

                                              Lucina Health

                                              Acquired by United Physician Management, December 2019

                                              NeuMoDx Molecular

                                              Acquired by QIAGEN, September 2020

                                              nVision Medical

                                              Acquired by Boston Scientific, April 2018

                                              NXThera

                                              Acquired by Boston Scientific, April 2018

                                              Rethink

                                              Acquired in January 2020

                                              SI-BONE

                                              Completed Initial Public Offering in October 2018

                                              Swift Biosciences

                                              Acquired by Integrated DNA Technologies, March 2021

                                              VasoNova

                                              Acquired by Teleflex Incorporated, January 2011

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